ICE21 is a device for physical treatment by cold which uses also different electric waves that produce different movements on muscle bundles; to obtain results like reduction of widespread or local fat, toning up and muscle recovery. Adipose fat cells are sensitive to cold, and at the working temperatures of the device; they undergo a process of slow and gradual spontaneous emptying called “apoptosis” (programmed cell death). The elimination of the lipids, located at interstitial level, from the human body is carried out by liver, gastrointestinal tract and lymphatic system, in approximately 15 days- 20 days.